Factors Associated with Adverse Events Related to Topical Whitening Products Used among College Female Students in Sudan
DOI:
https://doi.org/10.30829/contagion.v6i1.17927Abstract
This study aimed to explore the factors associated with adverse events related to topical whitening products used and to explore the reasons for using topical whitening products among female students in Sudan. A cross-sectional study was conducted from September to October 2023 in Sudan. The Medicine and Pharmacy programs were purposively selected as the study area. The total sample size was 208 participants. The self-administered questionnaire was constructed with a total of seventeen questions. For data analysis, we performed descriptive statistics analysis, bivariate analysis with simple logistic regression, and multivariable analysis with binary logistic regression presenting with adjusted odds ratio (AOR) and 95% confidence interval (95% CI). The results imply that students with middle household income were 93% less likely to get adverse events compared to those students with low household income with p-value = 0.030 (AOR: 0.07, 95% CI: 0.06 ,0.77). Students who have tested the topical whitening products before using them were 99.9% less likely to get adverse events compared to those who do not test, with p-value = <0.001 (AOR: 0.001, 95% CI: 0.001,0.00). Students who shared whitening products with family/friends were 89% less likely to get adverse events than those who do not share with p-value = 0.009 (AOR: 0.11, 95% CI: 0.021, 0.57). Furthermore, students who used whitening products with added water or other agents to whitening products were 95% less likely to get adverse events compared to those who did not use with p-value = 0.038 (AOR: 0.05, 95% CI:0.02, 0.84). The top two reasons respondents for using topical whitening products were acne (26.9%) and for beautification (24.5%). The study suggested the local government and health sectors should educate and raise the awareness of the safety of whitening products use among female students.Keywords: Adverse events, female students, Sudan, Whitening topical productsReferences
Addo, H. (2000). Squamous cell carcinoma associated with prolonged bleaching. Ghana Med J, 34(3), 144-146.
Agorku, E. S., Kwaansa-Ansah, E. E., Voegborlo, R. B., Amegbletor, P., & Opoku, F. (2016). Mercury and hydroquinone content of skin toning creams and cosmetic soaps, and the potential risks to the health of Ghanaian women. SpringerPlus, 5(1), 1-5.
Agorku, E. S., Kwaansa-Ansah, E. E., Voegborlo, R. B., Amegbletor, P., & Opoku, F. (2016). Mercury and hydroquinone content of skin toning creams and cosmetic soaps, and the potential risks to the health of Ghanaian women. SpringerPlus, 5, 319. doi:10.1186/s40064-016-1967-1
Ahmed, A. E., & Hamid, M. E. (2017). Use of Skin-Whitening Products by Sudanese Undergraduate Females: a Survey. Journal of Racial and Ethnic Health Disparities, 4(2), 149-155. doi:10.1007/s40615-016-0212-5
Alanzi, M. E., Alghamdi, R. A., Alsharif, O. M., Alghamdi, K. S., & El Sayed, S. M. (2018). Health Knowledge, Cosmetic Interests, Attitude, and the Need for Health Education Regarding the Use of Topical Bleaching Agents Among Women in West Saudi Arabia: A Cross-Sectional Study. J Cosmet Sci, 69(2), 101-120.
Andersen, F. A., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., . . . Snyder, P. W. (2010). Final amended safety assessment of hydroquinone as used in cosmetics. Int J Toxicol, 29(6 Suppl), 274s-287. doi:10.1177/1091581810385957
Bilal, A. I., Tilahun, Z., Osman, E. D., Mulugeta, A., Shekabdulahi, M., & Berhe, D. F. (2017). Cosmetics Use-Related Adverse Events and Determinants Among Jigjiga Town Residents, Eastern Ethiopia. Dermatol Ther (Heidelb), 7(1), 143-153. doi:10.1007/s13555-016-0157-y
Blay, Y. A. (2011). Skin bleaching and global white supremacy: By way of introduction. The Journal of Pan African Studies, 4(4), 4-46.
Bongiorno, M. R., & Aricò, M. (2005). Exogenous ochronosis and striae atrophicae following the use of bleaching creams. International journal of dermatology, 44(2), 112-115.
Chakera, A., Lasserson, D., Beck, L. H., Jr., Roberts, I. S., & Winearls, C. G. (2011). Membranous nephropathy after use of UK-manufactured skin creams containing mercury. Qjm, 104(10), 893-896. doi:10.1093/qjmed/hcq209
Charles, C. A. (2003). Skin bleaching, self-hate, and black identity in Jamaica. Journal of Black Studies, 33(6), 711-728.
Cheng, A.-D., De La Garza, H., Maymone, M. B., Johansen, V. M., & Vashi, N. A. (2021). Skin-Lightening Products: Consumer Preferences and Costs. Cureus, 13(8).
Dadzie, O. E., & Petit, A. (2009). Skin bleaching: highlighting the misuse of cutaneous depigmenting agents. Journal of the European Academy of Dermatology and Venereology, 23(7), 741-750.
Danish Khan, A., & Alam, M. (2019). Cosmetics and Their Associated Adverse Effects: A Review. Journal of Applied Pharmaceutical Sciences and Research, 2. doi:10.31069/japsr.v2i1.1
Dlova, N. C., Hamed, S. H., Tsoka-Gwegweni, J., & Grobler, A. (2015). Skin lightening practices: an epidemiological study of South African women of African and Indian ancestries. British Journal of Dermatology, 173(S2), 2-9.
Eagle, L., Dahl, S., & Low, D. R. (2014). Ethical issues in the marketing of skin lightening products.
Egbi, O. G., & Kasia, B. (2021). Prevalence, determinants and perception of use of skin lightening products among female medical undergraduates in Nigeria. Skin Health and Disease, 1(3), e46. doi:https://doi.org/10.1002/ski2.46
Getachew, M., & Tewelde, T. (2018). Cosmetic Use and Its Adverse Events among Female Employees of Jimma University, Southwest Ethiopia. Ethiop J Health Sci, 28(6), 717-724. doi:10.4314/ejhs.v28i6.6
Ho, Y. B., Abdullah, N. H., Hamsan, H., & Tan, E. S. S. (2017). Mercury contamination in facial skin lightening creams and its health risks to user. Regul Toxicol Pharmacol, 88, 72-76. doi:10.1016/j.yrtph.2017.05.018
Ibrahim, M. Q., Hassim, N., Yusof, A. A., & Abdul Mutalib, S. Z. (2015). Direct modelling CAD technology comparative review in efficiency and productivity for product development process. Applied Mechanics and Materials, 786, 305-310.
Iftekhar, N., & Zhitny, V. P. (2021). Overview of skin bleaching history and origins. Dermatology, 237(2), 306-308.
Khalil, R. A. (2022). Knowledge, Attitude and Practice of Skin Whitening Products, Among Sudanese Undergraduate Females, 2021. In: Research Square.
Lartey, M., Krampa, F. D., Abdul-Rahman, M., Quarcoo, N. L., Yamson, P., Hagan, P. G., . . . Adjei, A. A. (2017). Use of skin-lightening products among selected urban communities in Accra, Ghana. International journal of dermatology, 56(1), 32-39.
Lewis, K. M., Robkin, N., Gaska, K., & Njoki, L. C. (2011). Investigating motivations for women's skin bleaching in Tanzania. Psychology of Women Quarterly, 35(1), 29-37.
Lundov, M. D., Moesby, L., Zachariae, C., & Johansen, J. D. (2009). Contamination versus preservation of cosmetics: a review on legislation, usage, infections, and contact allergy. Contact Dermatitis, 60(2), 70-78. doi:https://doi.org/10.1111/j.1600-0536.2008.01501.x
Mahe, A., Ly, F., Aymard, G., & Dangou, J. M. (2003). Skin diseases associated with the cosmetic use of bleaching products in women from Dakar, Senegal. British Journal of Dermatology, 148(3), 493-500.
Mahé, A., Ly, F., & Perret, J.-L. (2005). Systemic complications of the cosmetic use of skin-bleaching products. International journal of dermatology, 44, 37-38.
Mahgoub, W. Y., Ibrahim, A. A., Mahgoub, J. Y., Ahmed, R., & Elmustafa, M. (2020). Reporting Adverse Reactions of Skin Whitening Products in Wad-Medani Dermatology Hospital, Sudan. Gezira Journal of Health Sciences, 16(1), 33-46.
Organization, W. H. (2019). Preventing disease through healthy environments: Mercury in skin lightening products. Retrieved from: https://iris.who.int/handle/10665/330015?&locale-attribute=ru
Osman, H., Shayoub, M., Ahmed, M. M., & Babiker, E. (2015). Assessment of using cosmetics containing hydroquinone among Sudanese women. Journal of Cosmetics, Dermatological Sciences and Applications, 5(02), 73.
Pollack, A. Z., Mumford, S. L., Krall, J. R., Carmichael, A. E., Sjaarda, L. A., Perkins, N. J., . . . Schisterman, E. F. (2018). Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach. Environ Int, 120, 137-144. doi:10.1016/j.envint.2018.07.028
Yusuf, M. A., Mahmoud, N. D., Rirash, F. R., Stoff, B. K., Liu, Y., & McMichael, J. R. (2019). Skin lightening practices, beliefs, and self-reported adverse effects among female health science students in Borama, Somaliland: A cross-sectional survey. Int J Womens Dermatol, 5(5), 349-355. doi:10.1016/j.ijwd.2019.08.006
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